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Molecular, Cellular, and Developmental Biology (MCDB)
Molecular, Cellular, and Developmental Biology (MCDB)
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Undergraduates
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All News
Search News
New Faculty Join MCDB
Monica Dus Named Rita Allen Foundation Scholar, Awarded $500,000
Protein folding on chaperone caught on video
Wang Lab Finds Key to Golgi Formation During Cell Divsion
Xu Lab Discovers Powerful Defense Against Free Radicals
Miller Lab Discovers Novel Ways Cell-Cell Junctions Are Maintained in Cytokinesis
Collins Lab Finds Connections Between Two Mediators of Axonal Repair
Fall Preview Weekend--Applications Now Open
MCDB Looking to Add Faculty in Neuroscience, Mathematical/computational biology
Bardwell Lab: Videogamers outdo scientists in contest to discover protein shape
NIH New Innovator Award for Dus
Wierzbicki Lab: New paper offers insights into mysterious world of non-coding RNAs
Nandakumar Lab: Mutation in Telomere protein TPP1 causes premature aging disease
Jakob Lab: researchers discover what makes drug for ulcerative colitis tick
Wittkopp Lab: Genetic basis of octanoic acid resistance in Drosophila sechellia
Kuwada Lab: critical roles for Stac3 in muscle contraction and human disease
The Science of Sleep
Sloan Fellowships for Dus & Stockbridge
Aton Lab: Rhythmic firing of neurons needed for memory formation
Xu Lab: New target for heartburn treatment identified
MCDB welcomes our newest graduate students
Denver Lab: Study sheds light on relationship between environment, hormones and evolution
Chapman Lab: Protein Could Help Fight Antibiotic Resistance
Collins Lab: Pathway in neurons may contribute to neurodegenerative disease
Aton Lab: Deep sleep critical for visual learning
Wierzbicki Lab: Long-range control of gene expression via RNA-directed DNA methylation
Nandakumar Lab: Dissecting the telomere–inner nuclear membrane interface formed in meiosis
Nandakumar Lab: Second region on TPP1 assists in binding telomerase to chromosomes
2018 Sloan Research Fellowship for Clowney
Shafer Lab: Drosophila tune into environmental temperature to time sleep
Denver Lab: Fat-sensing hormone helps control tadpole metamorphosis
Wang Lab: Novel energy sensor in Golgi regulates autophagy
MCDB Moving to New BSB
Meet our 2018 Entering Class of Graduate Students
Denver Elected AAAS Fellow
Bringing Advanced Biology to Northern Michigan High School Students
Miller Lab: Rho flares repair local tight junction leaks
Vecchiarelli Lab: A “Blue” and “Green” collaboration probing “blue-green algae”
May 6 Connell Symposium "Breakthroughs in Biology"
Dus Lab Fly Study: High-Sugar Diet Deadens Sweet Tooth
Bo Duan Lab: Scratch that itch
Jakob Lab: Oxidative stress in early life extends lifespan
Nandakumar Lab: How Human Telomerase Binds to Telomere
New year, new titles, and a fond farewell
UM targets muscular dystrophy in mice
Csankovszki Named Thurnau Professor
Research Blooms for Student Working on Peony Genetics
New Lecturers, New Students Join MCDB
Buttitta Lab: Accumulating extra genome copies may protect fly brain cells during aging
Wierzbicki Lab: Noncoding RNA may play an essential role in protecting the integrity of the genome
Dus Lab: Sugar Remodels Molecular Memory in Fruit Flies
Jakob Elected AAAS Fellow
Giving Blueday March 10
Aton Lab: Sleep is vital to associating emotion with memories
Neuroscience Undergrads Explore Research Pathways
Clowney Named 2021 Pew Scholar
Chang and Nielsen Promoted
Nandakumar Lab: researchers solve structure of protein complex important in DNA repair
Developing Future Biologists Earn Diversity Award
Awards for MCDB Trainees Recognize Excellence
Denver and Pichersky to Retire
Miller Lab: researchers create artificial cell cortex, a system to study how cells divide
Bacterial genome is regulated by an ancient molecule
From The Conversation
Bitten By Sugar
Südhof to present 2022 Connell Lecture
Expanding Horizons: MCDB's summer intern program removes barriers to undergrad research
MCDB Faculty Promoted
MCDB Opens Search for Faculty
MCDB Scientists-in-Training Garner Awards
Ming Li Lab: Missing pathway in lysosome underlies newly discovered human disease
Xu Lab: New molecular mechanism for Parkinson’s disease risk
Dus Lab: A high-sugar diet dulls rats sense of sweetness taste
Publication Spotlight: Jakob Lab, Cover of Molecular Cell
Publication Spotlight: Miller Lab cover for MBoC
MSBT “Amplifying” their education while solving global challenges
Bardwell and Frydman on visualization of chaperone-mediated protein folding
Chapman Elected to American Microbiology Academy
Maria Ahmed Named a 2023 Weintraub Award Recipient
Counter-Culture: The art and science of microbes
Aton Lab: ‘Binocular’ treatment helps with a common vision problem
Dus Awarded Guggenheim Fellowship
Finding clues about the process of cell plasticity
Simmons Lab: New protein important for replication of the lagging strand in bacteria
Nandakumar Lab: A POT-hole that protects our chromosome ends
Ming Li Lab: Rare disease shares mechanism with cystic fibrosis
MCDB Professor Named White House Fellow
Jakob Lab: Early life changes protective against age-related amyloid toxicities
Better Understanding of Science Through Creative Works
New from Shan Lab: When plants are attacked
MCDB Merch Available
Researchers uncover protein responsible for cold sensation
Different means to the same end: How a worm protects its chromosomes
Regents Approve Five MCDB Faculty Promotions
Wierzbicki Lab: Organization of the chloroplast nucleoid structure
Anti-Racism Research & Community Impact Faculty Fellowship for Ariangela Kozik
Jakob Lab: Redox and the Fate of Embryonic Stem Cells
Miller Lab: Vinculin maintains junction integrity and barrier function at epithelial tricellular junctions
Studying plant DNA in a war zone
Finding a missing piece for neurodegenerative disease research
MCDB's Kozik Honored by Microbiology Society
Archived News
2016
March 2016
Prestigious Rackham Fellowship for MCDB's Xu Liu
February 2016
MCDB/UM Field Hockey star Alum featured on MGoBlue
Mr. Autophagy--MCDB's Klionsky profiled in LSI Magazine
Novel regulator of Wnt/ß-catenin signaling discovered
MacAlister Awarded 2016 Early Career Award
2015
October 2015
MCDB scientists talk about CRISPR in LSA Magazine "Genetic Friend or Fiend?"
"The Gene Team" Michigan Synthetic Biology Team featured in LSA Fall Magazine
New Faculty Search Underway
U-M Faculty Recognition Award to Xu
August 2015
Dus proposal funded by MiBrain initiative at University of Michigan
June 2015
Research by MCDB Professor Helps to Explain Why Diet Foods Don't Seem to Help Regulate Weight
Regular soda, please: Hormone that differentiates sugar, diet sweeteners could exist in humans
"Mysteries of the Brain" from NBC Learn and NSF features MCDB's Shafer in "Brain States" segment
May 2015
MCDB Faculty Promoted
Taylor Nye (Simmons Lab) Garners Best Undergraduate Thesis Award
UROP Summer Fellowship Provides Jalal Taleb with Research Opportunity in Dus Lab
April 2015
Undergraduates in Biology and Neuroscience Present Work at Poster Session
Pichersky Awarded Guggenheim
NSF Graduate Research Fellowships to Three in MCDB Labs
More MCDB Students Awarded Predoctoral Fellowships
March 2015
Miller Lab Student Awarded Rackham Predoctoral Fellowship
Selection on noise constrains variation in a eukaryotic promoter
January 2015
3Science Cafe: Shining Light on the Brain
Bacteria have a potent, selective inhibitor of amyloid formation
2014
December 2014
MCDB alum, now a microbiologist fighting Ebola in Liberia, featured in NYTimes
Rescuing the golgi puts brakes on Alzheimer’s progress
New Biological Sciences Building A Step Closer
September 2014
Disease decoded: Gene mutation may lead to development of new cancer drugs
Versatile protein helps cells survive oxidative stress
Potential treatment for muscular dystrophy: target muscle repair
Klionsky named one of "World's Most Influential Minds"
August 2014
MCDB Undergraduate Earns Award at Recent Bacterial Genetics Conference
July 2014
Yocum on team illuminating role of vibration in photosynthesis
Simmons selected for LSA Teaching Award
Miller lab paper featured on Current Biology website
June 2014
Endocrine Society awards for two graduate students in Denver Lab
PIBS Research Award to MCDB's Zepeng Yao
May 2014
Discovery of protein that regulates cellular recycling yields new drug targets
MCDB graduate student earns award at midwest DNA repair meeting
Simmons Lab Undergraduate Co-first Author on <i>Journal of Bacteriology</i> article
April 2014
Senior MCDB Honors Student Haggadone to Receive Award
Boles lab: Triclosan Promotes Staphylococcus aureus Nasal Colonization
3 NSF Graduate Fellowship winners in MDCB
March 2014
Shafer lab: circadian clock is like an orchestra with many conductors
MCDB work appears in science journal covers exhibit at Shapiro Library
LSA Biologists Yanzhuang Wang And Gunjan Joshi Discover A Method To Slow The Growth Of Alzheimer's Cell-Killing Plaques
UM scientists slow development of Alzheimer's trademark cell-killing plaques
Jakob elected to Bavarian Academy of Sciences and Humanities
February 2014
Chemical chaperones have helped proteins do their jobs for billions of years
January 2014
MCDB department chair champions women in science
Synthetic Biology Team: UM students program bacterial cells to make computer-like decisions
2013
December 2013
Zebrafish help decode link between calcium deficiency and colon cancer
MCDB joins E2Coach project
MCDB Lecturer Role Model for UM Softball's Katie Luetkens
November 2013
Engaging Girls in STEM Fields with Help from MCDB
September 2013
NIH Innovator award to Sara Aton for research on brain changes during sleep
August 2013
Learning how the brain takes out its trash may help decode neurological diseases
June 2013
Zebrafish Help Identify Mutant Gene in Rare Muscle Disease
March 2013
Stressed-out Tadpoles Grow Larger Tails to Escape Predators
February 2013
MCDB Assistant Professor Sara Aton Awarded Sloan Foundation Grant
Student Biologists Use Diag Trees to Help Solve Gypsy Moth Mystery
MCDB Launches New Website
January 2013
Elaina Breznau of Miller Lab awarded a Journal of Cell Science Travelling Fellowship
Lilia Popova Selected as 2013 Intel Science Talent Search Finalist
2012
November 2012
Adnan Syed Awarded American Heart Association Predoctoral Fellowship
MCDB Professors Named American Association for the Advancement of Science (AAAS) Fellows
In Memoriam - Professor Emeritus Sally Allen
Zepeng Yao Nominated for HHMI Research Fellowship
USB Teaching Laboratory Receives the Sustainable Lab Recognition Program Silver Award
Department Welcomes Courtney Long
October 2012
Elaina Breznau Awarded Rackham Graduate Student Research Expense Grant
Welcome New Staff
Aaron Talsma Working in Vienna Under Fulbright Fellowship
How can we study evolution if the process takes thousands of years?
Michigan's Synthetic Biology Team Earns Gold at iGEM Americas East Regional
Ed Grant, a.k.a. Ed Kraus, Retires
How Ford is Trying to Make Cars Stink Less&mdash;Literally
Xiang Wang and Xiaoli Zhang Discover New Ion channels in the Lysosome
Linda Foit and Researchers Found Interdisciplinary Workshop InSPIRE
Wittkopp chosen to help create UT Academy of Distinguished Teachers
September 2012
Graduate Student Mohammed Samie Receives Best Poster Award
MCDB Professors Receive Back-to-Back Comprehensive Reviews
Nicholas Bolz's Thesis Published in <i>Journal of Bacteriology</i>
M-Bio Wraps Up Second Successful Summer
All Events
Archived Events
2016
April 2016
Manipulation of Plant Defenses by Aphids: Spit Matters
Mechanisms and Fidelity of DNA and RNA Ligation
TBA
March 2016
TBA
13th Annual Connell Memorial Lecture
Building the Body Plan: The Miracle of Morphogenesis
Regulation of Energy Homeostasis by Physiological ER Stress Response
February 2016
Genetic Regulation of Growth and Regeneration
The COG Complex Functions in Trafficking of Glycosyltransferases and Bacterial Toxins Through the Golgi
Faculty Candidate: Genetic Dissection of Neural Circuits Processing Pain and Itch
Faculty Candidate: The neurogenetic origins of behavioral diversity and collective consensus in Drosophila
January 2016
Faculty Candidate: Uncovering the Epitranscriptome: Dynamic mRNA Methylation & Gene Expression Control
Faculty Candidate: Perception, Behavior, and the Dynamics of the Awake State
Faculty Candidate: The Biology, Mechanism, & Application of Meningococcal CRISPR-Cas9
Faculty Candidate: Found in Translation: The Ribosome and its Impact on mRNA Stability
Faculty Candidate: Mechanisms Producing Fixed & Flexible Processing in Chemosensory Circuits
Faculty Candidate: Organizing the Cell with Dynamic Protein Gradients
Faculty Candidate: Molecular Control of Meiotic Chromosome Dynamics
Faculty Candidate: Evolution and Development of our Closest Invertebrate Relatives, the Tunicates
2015
December 2015
Faculty Candidate: Trafficking & Turnover of Lysosomal Membrane Proteins
Faculty Candidate: Dynamic Sensory Representations in Auditory Cortex
A Molecular Mechanism to Regulate Lysosome Motility for Lysosome Positioning and Tubulation
November 2015
Epigenetic Mechanisms in Memory Formation
Developing the Sensorimotor System in our Sleep
October 2015
Genetic Manipulations in the Fruit Fly Fight Club: How do Amine Neurons Work Studied at a Single Neuron Level
Functions and Applications of CRISPR-Cas Immune Systems
Role of Thalamus in Physiological and Pathological EEG Rhythms
Cell Wall Dynamics and Evolution in Eukaryotic Microbes: Hydroxyproline-Rich Glycoproteins and Eisosomes
Computational Strategies for Decoding Endogenous Plant Promoter Sequences
September 2015
Osteoblasts and Energy Metabolism: Why Bone Counts Calories
Uncovering the Nuts and Bolts of the Genetic Determination of Skeletal Cell Types: A Key Step Towards Improving Therapeutic Approaches for Bone and Cartilage Diseases
Telomerase Biogenesis and Regulation in Fission Yeast and Human Cells
June 2015
Crosstalk Between the Plant Splicing Machinery and Microprocessor in the Regulation of MicroRNA Expression
May 2015
Sending a Message: Cbk1/Ndr Kinase Signaling and Spatial Regulation of mRNA
Beyond Scaffolding: Histone Variants as Road Map Providers for Genomic Activities
April 2015
Connell Memorial Lecture
Reception-Through the Magnifying Glass: A Short History of the Microscope
Interplay Between Replication and Transcription in Bacteria
Design principles and control in biological systems
Towards Enhanced Understanding of Protein Folding in the Cell
Through the Magnifying Glass: A Short History of the Microscope
Hypoxia, Metabolism, and Tumor Progression
March 2015
Tricellular tight junctions: how the extracellular space is sealed where three epithelial cells meet
Regulation of Chromatin Structure and Transcription in <i>C. elegans</i>
Update on the REBUILD Project
February 2015
Host-Microbiome Interactions in Pulmonary Health and Disease
Ultrafast Recycling of Synaptic Vesicles
January 2015
Science Cafe: Shining Light on the Brain
How to Win Partners and Influence Synapses: Understanding Neuronal Organization on the Fly
Microbial resistance to toxic fluoride: structural and functional features of fluoride channels and transporters
Coordination of Vertebrate Post-Embryonic Development
Molecular Design Principles of Protein Synthesis
How Beta-Lactam Antibiotics Kill Bacteria
Neuronal Circuits Controlling the Formation and Recollection of Fear Memory
2014
December 2014
Neural Mechanisms of Social Behavior
Chaperone Discovery
November 2014
Genetic Analysis of Neural Circuits that Regulate Fear and Aggression
Drosophila Ack Family Kinases Regulate Sperm Development
The Role of Telomere Cohesion in ALT Tumor Cells
October 2014
Revelations About Genes and Gene Therapy From A Bicistronic Calcium Channel Gene
Reverse-engineering the Mechanics of Morphogenesis
Regulated Chromatin Remodeling During Transcription and Development
Engineering Histone Gene Clusters to Interrogate Epigenetic Control of the Cell Cycle During Animal Development
September 2014
REBUILD Seminar
Gating Reliable Neurotransmission: Implications for Synaptic Homeostasis and Migraine
May 2014
Priscilla Connell Memorial Lecture: Molecular, Cellular, and Developmental Mechanisms of Oxygen Homeostasis
Lysosomal signaling controls cellular homeostasis
MCDB Faculty Noon Seminar
April 2014
CANCELLED: Hypoxia, Metabolism, and Tumor Progression
Drosophila, Social Interactions, and Timing
MCDB Junior Faculty Forum
A View to a Kill: the Bacterial Type VI Secretion System
March 2014
MCDB Junior Faculty Forum
Exploiting Natural Products to Probe Pain Receptors
Antibodies By Design
How cells maintain health through self-eating
Fishing in the Dark: Understanding melanoma and melanocyte biology using the zebrafish
MCDB Faculty Noon Seminar
Planar Cell Polarity: from Cell Biology to Human Disease
Peptide: N-glycanase and non-lysosomal degradation of glycans: Basic science meets a human genetic disease
January 2014
Spinal microcircuits in fish suggest an evolutionary template for limb control
Balancing taste and calories in feeding: a fly's perspective
Making the right decision: Repairing DNA breaks during <i>C. elgans</i> meiosis
2013
December 2013
Developmental timing and decision making in plants
Modeling mitochrondrial stress signaling in Drosphila: A platform for therapeutic discovery
Biogenesis of a carbon-fixing bacterial organelle
Heritable epigenetics of complex traits in C. elegans
Controlling responses to oxygen deprivation and restoration: from genes to cells to behavior
Microbial Warfare: Evolutionary dynamics between epidemic Vibrio cholerae and a predatory phage
November 2013
Using the Worm to Catch Zs: Somnogen Discovery in C. elegans
MCDB Faculty Noon Seminar
VHL Tumor Suppressor Protein in the Mammalian Oxygen-Sensing Pathway
UM Autophagy Dance collaboration on TV's "Detroit Performs"
Characterization of Weak Protein-Protein Interactions in DNA Replication and Repair
MCDB Junior Faculty Forum
Roles of the Crb-Nok-Lin7 Apical Polarity Protein Complex in Neural Development
October 2013
Myc: More Than Just a Transcription Factor
How JNK FAScilitates Neuronal Remodeling
MCDB Faculty Noon Seminar
Synaptic Transmission at Photoreceptor Ribbon Synapses
Evolution and Function of DNA Methylation in the Context of Chromatin
Mechanisms of Chromosomal Instability in Human Cancer Cells
MCDB Junior Faculty Forum
Cytoplasmic Glycosylation Targets a Polyubiquitin Ligase to Control Oxygen Sensing in Protists
September 2013
Synapse Formation and Plasticity and Implications in Muscular Dystrophy and Schizophrenia
MCDB Faculty Noon Seminar
Mechanisms of Synchronization in the Circadian Neural Circuits of Drosophila
Conjugation of ISG15 and Ubiquitin at the Ribosome
Histone Modifying Enzymes in Cell Proliferation and Development
May 2013
MCDB Faculty Lunch Mtg. - Research Update
April 2013
MCDB Faculty Lunch Mtg. - Research Update
The Tenth Annual Priscilla Connell Memorial Lecture
Neural Network Adaptation in the Retina: Dopamine and Circadian Mechanisms
Walking the Highwire from Synaptic Growth to the Axonal Injury Response
March 2013
Allosteric Gating of Voltage and Calcium Activated Potassium Channels
MCDB Jr. Faculty Lunch Seminar - Undergraduate Curriculum Discussion
Studies of Eukaryotic DNA Replication Fidelity
Chromatin Remodeling During Reproductive Development in Arabidopsis
MCDB Faculty Lunch - LSA High Performance Computing
DNA Maintenance in Genetic Stability and Cell Cycle Control
February 2013
MCDB Faculty Lunch Meeting - Single Molecule Imaging (SMART) Center
January 2013
Surviving Without Food
Local Circuitry Mechanism Regulating Adult Neurogenesis
Roles of the Telomere Protein Complex POT1-TPP1 in Chromosome End Protection and End Replication
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Biochemistry
Cell Biology
Development
Microbiology
Neurobiology and Animal Physiology
Plant Molecular Biology
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Ask A Biologist
Recent Publications
Miller Lab: Role of Vinculin in Tricellular Junctions
Jakob Lab: Embryonic Stem Cell Fate
Wierzbicki Lab: Membrane association of active genes organizes the chloroplast nucleoid structure
Shan Lab: Dual phosphorylation of DGK5-mediated PA burst regulates ROS in plant immunity
Simmons Lab: Bacillus subtilis encodes a discrete flap endonuclease that cleaves RNA-DNA hybrids
DeSantis/Nandakumar Labs: KASH5 protein
Cadigan Lab: SOX9 and TCF transcription factors associate to mediate Wnt/β-catenin target gene activation in colorectal cancer
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Molecular, Cellular, and Developmental Biology (MCDB)
2220 Biological Sciences Building
1105 North University Ave.
Ann Arbor, MI 48109-1085
Prospective undergrads: Please contact the Program in Biology 734-763-7984, lsa-biology-advising@umich.edu | | |

Graduate students: Grad Coordinator 734-615-1635 | | |

Chair's office: 734-764-7427

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