High-resolution Fluorescence Microscopy * Super-resolution Imaging * Single Particle Imaging and Tracking * Fluorescence Lifetime Imaging * Fluorescence Correlation Spectroscopy * Atomic Force Microscopy * Optical Tweezers
Welcome to the SMART Center: Single Molecule Analysis in Real-Time!
The SMART Center is an NSF-seeded microscopy core facility that provides advanced tools that help researchers see, track, move, and study biomolecules in great detail.
The center supports research using techniques such as:
- High-resolution fluorescence microscopy
- Super-resolution imaging
- Single-particle imaging and tracking
- Fluorescence lifetime imaging
- Fluorescence correlation spectroscopy
- Atomic force microscopy
- Optical tweezers
About the SMART Center
The SMART Center provides University of Michigan researchers with access to advanced imaging and molecular manipulation tools.
The center offers:
- Training on instruments and methods
- Support with data collection
- Help with experimental design
- Help with data analysis
- Consultation from experienced staff
The SMART Center also works to support a university-wide effort in single-molecule technology. This includes methods such as:
- Single-molecule spectroscopy, also called SMS
- Single-molecule imaging, also called SMI
- Laser tweezers, also called LT
- Atomic force microscopy, also called AFM
These tools help researchers study important questions in areas such as medicine, biology, engineering, chemistry, physics, and nanotechnology.
The center serves:
- University of Michigan researchers
- External academic researchers
- Commercial researchers
The SMART Center supports research across many scientific fields, with a special focus on RNA biomedicine.
Open Consultations
Open consultations are available:
Mondays and Thursdays, 10:00 a.m. to 12:00 p.m.
Location: CHEM 3080
Researchers are welcome to stop by for a short presentation and brainstorming session. These sessions can help you explore how SMART Center tools may support your research.
Specialized Techniques
The center offers several advanced spectroscopy and imaging methods.
To schedule time on an instrument or submit a project request, visit our MiCORES Reservation System. If you do not have a MiCORES account, see instructions to register on the Rates and Requesting Time page.
SMART Center Contacts
| Damon Hoff | SMART Center Manager | CHEM 3080 | (734) 763-5449 | hoffj@umich.edu |
| Nils Walter | SMART Center Director | CHEM 2405 | (734) 615-2060 | nwalter@umich.edu |
