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Mucinomics as the next frontier of mass spectrometry

Stacy Malaker (Yale University)
Thursday, December 7, 2023
4:00-5:15 PM
1640 Chemistry Dow Lab Map
Mucin-domain glycoproteins are densely O-glycosylated and play key roles in a host of biological functions. However, their dense O-glycosylation remains enigmatic both in glycoproteomic landscape and structural dynamics, primarily due to the challenges associated with studying mucin domains. Here, we present advances in the mass spectrometric analysis of mucins, including the characterization of mucinases, software comparisons, and complete mucinomic mapping of translationally relevant mucin proteins.
Building: Chemistry Dow Lab
Event Type: Workshop / Seminar
Tags: Analytical Chemistry, Chemistry, Science
Source: Happening @ Michigan from Department of Chemistry, Analytical Chemistry