Assistant Professor of Psychology
About
****Annelise Madison is accepting a PhD student in the clinical science area for Fall 2025.*****
Additional Research Interests:
Psychoneuroimmunology, Gut-Brain Axis
Annelise A. Madison is a Tenure-Track Assistant Professor of Psychology (Clinical Science area) and affiliate member of the Eisenberg Family Depression Center at the University of Michigan. She is interested in psycho-neuro-immunology (mind-brain-immune connections) as a lens to develop preventative interventions for inflammatory disorders, including autoimmune disease and some cases of depression. By bridging the gap between clinical science and psychoneuroimmunology, psychology can become a first-line tool of medicine, with potential to impact disease onset, severity, trajectory, and treatment efficacy. As the gut plays a role in immune function, her work also includes exploration of the gut-brain axis. Zooming out, she is interested in a pathway from social stress to immune dysregulation to increased risk for psychopathology (especially depression). Her lab includes work that is mechanistic (e.g., using laboratory stress paradigms and other immune stimuli to provoke a physiological and emotional response and examine psychosocial factors that moderate this response), as well as applied (e.g., implementing an EBT for depression at the start of biologic treatment for rheumatoid arthritis to improve treatment outcomes.) Her research exists at the nexus of psychology and medicine.
Representative Publications:
Madison, A.A., Bailey, M.T. (2024). Stressed to the Core: Inflammation and Intestinal Permeability Link Stress-Related Gut Microbiota Shifts to Mental Health Outcomes. Biological Psychiatry, 95(4), 339-347.
Madison, A.A., Kiecolt-Glaser, J.K., Malarkey, W.B., Belury, M.A. (2023). Omega-3 fatty acids reduce depressive symptoms only among the socially stressed: A corollary of the Social Signal Transduction Theory of Depression. Health Psychology, 42(7), 448-459.
Madison, A.A., Renna, M.E., Andridge, R.A., Peng, J., Shrout, M.R., Sheridan, J., Lustberg, M., Ramaswamy, B., Wesolowski, R., Williams, N.O., Noonan, A.M., Reinbolt, R.E., Stover, D.G., Cherian, M.A., Malarkey, W.B., Kiecolt-Glaser., J.K. (2023). Conflicts hurt: Social stress predicts elevated pain and sadness following mild inflammatory increases. Pain, 164(9), 1984-1994.
Madison, A.A., Way, B., Ratner, K., Renna, M.E., Andridge, R., Peng, J., Shrout, M.R., Sheridan, J., Lustberg, M., Ramaswamy, B., Wesolowski, R., VanDeusen, J.B., Williams, N.O., Sardesai, S.D., Noonan, A.M., Reinbolt, R.E., Stover, D.G., Cherian, M.A., Malarkey, W.B., Kiecolt-Glaser, J.K. (2022). Typhoid vaccine does not impact feelings of social connection or implicit or explicit social behavior in a randomized, placebo-controlled trial among middle-aged women. Brain, Behavior, and Immunity, 107: 124-131.
Madison, A.A., Andridge, R., Shrout, M.R., Renna, M.E., Bennett, J.M., Jaremka, L.M., Fagundes, C.P, Belury, M.A., Malarkey, W.B., Kiecolt-Glaser, J.K. (2021). Frequent interpersonal stress and inflammatory reactivity predict depressive symptom increases: Two tests of the Social Signal Transduction Theory of Depression. Psychological Science, 33(1), 152-164.
Madison, A.A., Belury, M.A., Andridge, R., Renna, M.E., Shrout, M.R., Malarkey, W.B., Lin, J., Epel, E.S., Kiecolt-Glaser, J.K (2021). Omega-3 supplementation and stress reactivity of cellular aging biomarkers: An ancillary substudy of a randomized, controlled trial in midlife adults. Molecular Psychiatry, 26(7), 3034-3042.
Madison, A.A, Andridge, R., Padin, A., Wilson, S., Bailey, M., Alfano, C., Povoski, S., Lipari, A., Agnese, D., Carson, W., Malarkey, W., Kiecolt-Glaser, J.K. (2020). Endotoxemia coupled with heightened inflammation predicts future depressive symptoms. Psychoneuroendocrinology, 122, 104864.
Madison, A.A., Belury, M.A., Andridge, R., Shrout, M.R., Renna, M.E., Malarkey, W.B., Bailey, M.T., Kiecolt-Glaser, J.K. (2020). Afternoon distraction: A high saturated fat meal and endotoxemia impact post-meal attention in a randomized crossover trial. The American Journal of Clinical Nutrition, 111(6), 1150-1158.
