More than a quarter of medical school students report depressive symptoms or depression, while about one in 10 experiences suicidal thoughts, according to a new analysis in the Journal of the American Medical Association. The analysis reviewed nearly 200 studies involving more than 129,000 students in 47 countries.

Depression is "an open secret" in the profession, said Dr. Douglas Mata, co-principle author, a resident physician at Brigham and Women's Hospital and a clinical fellow at Harvard Medical School.

These calculations are more than just numbers to co-principle author Dr. Srijan Sen.

"When I was a medical student, a couple of people just a little bit older than me really suffered with depression and had serious suicide attempts, and one of them completed suicide," said Sen, a professor of depression and neurosciences at the University of Michigan. "It hit home to me and made me realize how big a problem this was and was part of the reason why I got involved in this research."

Read the full article "Study: More than a quarter of medical students are depressed, suicidal" at CNN.