Depression has been traditionally treated globally as a disorder of brain chemistry. But what if the immune system is pulling more strings than we ever realized?

A new University of Michigan and Harvard University systematic review and meta-analysis finds that anti-inflammatory treatments not only reduce depressive symptoms, but also anhedonia—the inability to feel pleasure—in people with both depression and high levels of inflammation. 

“This is an important finding that has the potential to make the emerging field of immunopsychiatry more relevant,” said the study’s co-first author Annelise Madison, assistant professor of clinical psychology and affiliate member in the U-M Eisenberg Family Depression Center.


Read the complete article in Michigan News