About
James McCormick is a scholar of Bioinformatics and Biophysics. His research focuses on protein engineering, computational drug discovery, and understanding the process of allostery: the long range communication across a protein.
As a lecturer in the Program in Computing for the Arts and Sciences at the University of Michigan, he teaches courses on computing for digital media and programming for the sciences. James has two dogs: Finnegan and Jake.
Academic Publications:
Computationally accelerated identification of P-glycoprotein inhibitors. PLOS ONE. PMID: 40802735 (2025)
Engineering proteins using statistical models of co-evolutionary sequence information. Machine Learning for Protein Science and Engineering. Cold Spring Harb Perspect. Biol PMID: 38110247 (2023)
Structurally Distributed Surface Sites Tune Allosteric Regulation. eLife. PMID: 34132193. (2021)
Transport of Alzheimer's associated amyloid-β catalyzed by P-glycoprotein. PLOS One, PMID: 33901197 (2021)
Strategies for Engineering and Rewiring Kinase Regulation. Trends Biochem Sci. PMID: 31866305. (2019)
Multiple Drug Transport Pathways through Human P-Glycoprotein. Biochemistry. PMID: 26125482 (2015)
